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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Inhibition of Drp1 downregulates global autophagy rather than mitophagy [204]

Histochem Cell Biol 2022;158:213-27

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One Mg 2+ ion coordinates motif C and binds at the 3 end (i site) of the RNA primer, facilitating the condensation reaction in RNA chain synthesis, while the second Mg 2+ positions the incoming NTP and stabilizes the charge environment